Evaluation of the pol/S Gene Overlapping Mutations in Chronic Hepatitis B Patients in Northern Cyprus

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Polish Journal of Microbiology

Polish Society of Microbiologists

Subject: Microbiology

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ISSN: 1733-1331
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VOLUME 68 , ISSUE 4 (Jan 2019) > List of articles

Evaluation of the pol/S Gene Overlapping Mutations in Chronic Hepatitis B Patients in Northern Cyprus

AYSE ARIKAN * / MURAT SAYAN / TAMER SANLIDAG / KAYA SUER / SINEM AKCALI / MERYEM GUVENIR

Keywords : Drug resistance, mutations, hepatitis B, Northern Cyprus

Citation Information : Polish Journal of Microbiology. Volume 68, Issue 4, Pages 317-322, DOI: https://doi.org/10.33073/pjm-2019-034

License : (CC-BY-4.0)

Published Online: 03-September-2019

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  1. Ahn SH, Kim DH, Lee AR, Kim BK, Park YK, Park ES, Ahn SH, Shin GC, Park S, Kang HS, et al. Substitution at rt269 in hepatitis B virus polymerase Is a compensatory mutation associated with multi-drug resistance. PLoS One. 2015;10(8):e0136728. https://doi.org/10.1371/journal.pone.0136728
    [CROSSREF]
  2. Altindïş M, Aslan FG, Köroğlu M, Eren A, Demïr L, Uslan Mİ, Aslan S, Özdemïr M, Baykan M. Hepatitis B virus carrying drug resistance compensatory mutations in chronically infected treatment naïve patients. Viral Hepatit Dergisi. 2016;22(3):103–107. https://doi.org/10.4274/vhd.07830
    [CROSSREF]
  3. Altindis M, Yilmaz S, Dikengil T, Acemoglu H, Hosoglu S. Serop-revalence and genotyping of hepatitis B, hepatitis C and HIV among healthy population and Turkish soldiers in Northern Cyprus. World J Gastroenterol. 2006;12(42):6792–6796. https://doi.org/10.3748/wjg.v12.i42.6792
    [CROSSREF]
  4. Arikan A, Şanlidağ T, Süer K, Sayan M, Akçali S, Güler E. [Molecular epidemiology of hepatitis B virus in Northern Cyprus] (in Turkish). Mikrobiyol Bul. 2016;50(1):86–93. https://doi.org/10.5578/mb.10292
    [CROSSREF]
  5. Asan A, Sayan M, Akhan S, Tekin Koruk S, Aygen B, Sirmatel F, Eraksoy H, Tuna N, Köse S, Kaya A, et al. Molecular characterization of drug resistance in hepatitis B viruses isolated from patients with chronical infection in Turkey. Hepat Mon. 2018;18(1):e12472. https://doi.org/10.5812/hepatmon.12472
    [CROSSREF]
  6. Avellón A, Echevarria JM. Frequency of hepatitis B virus ‘a’ determinant variants in unselected Spanish chronic carriers. J Med Virol. 2006;78(1):24–36. https://doi.org/10.1002/jmv.20516
    [PUBMED] [CROSSREF]
  7. Bottecchia M, Barcaiu HS, Lewis-Ximenez LL, da Silva e Mouta Junior S, de Moraes MTB. Monitoring the emergence of HBV resistance mutations by HBV-RNA pyrosequencing. Braz J Infect Dis. 2016;20(2):216–217. https://doi.org/10.1016/j.bjid.2015.11.004
    [PUBMED] [CROSSREF]
  8. Caligiuri P, Cerruti R, Icardi G, Bruzzone B. Overview of hepatitis B virus mutations and their implications in the management of infection. World J Gastroenterol. 2016;22(1):145–154. https://doi.org/10.3748/wjg.v22.i1.145
    [PUBMED] [CROSSREF]
  9. Choi YM, Lee SY, Kim BJ. Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. World J Gastroenterol. 2018;24(16):1708–1724. https://doi.org/10.3748/wjg.v24.i16.1708
    [PUBMED] [CROSSREF]
  10. Guler E, Suer K, Arikan A, Guvenir M, Sanlidag T. Seroprevelance of Hepatitis B Virus, Hepatitits C Virus and Human Immunodeficiency Virus in Northern Cyprus. Bakirkoy Med J. 2018;14:332–338.
    [CROSSREF]
  11. Gürsoy NC, Otlu B, Yakupogulları Y, Yener Ö, Bayındır Y, Harputluoglu M, Tekerekoglu MS. Nucleos(t)ide resistance mutations in chronic HBV patients with treatment failure. Türk Mikrobiyoloji Cemiyeti Dergisi. 2019;49(1):41–46. https://doi.org/10.5222/TMCD.2019.041
  12. Lapiński TW, Parfieniuk-Kowerda A, Trzos A, Jaroszewicz J, Kowalczuk O, Nikliński J, Flisiak R. HBV mutations associated with lamivudine therapy. Przegl Epidemiol. 2013;67:611–616.
    [PUBMED]
  13. Lazarevic I. Clinical implications of hepatitis B virus mutations: recent advances. World J Gastroenterol. 2014;20(24):7653–7664. https://doi.org/10.3748/wjg.v20.i24.7653
    [CROSSREF]
  14. Lin CL, Chien RN, Hu CC, Lai MW, Yeh CT. Identification of hepatitis B virus rtS117F substitution as a compensatory mutation for rtM204I during lamivudine therapy. J Antimicrob Chemother. 2012;67(1):39–48. https://doi.org/10.1093/jac/dkr416
    [PUBMED] [CROSSREF]
  15. Mahmood M, Anwar MA. Analysis of resistant mutations in reverse transcriptase domain of hepatitis B virus from patients from Islamabad, Pakistan. J Unexplored Med Data. 2017;2(2):60–64. https://doi.org/10.20517/2572-8180.2017.13
    [CROSSREF]
  16. Ozguler M, Sayan M. Could resistant and escape variants of hepatitis B virus be a problem in the future? Future Virol. 2018;13(3):171–179. https://doi.org/10.2217/fvl-2017-0144
    [CROSSREF]
  17. Ozguler M, Sayan M. Growing threat: vaccine escape mutant hepatitis B viruses. ARC J of Immunology and Vaccines. 2016;1(1):9–17.
  18. Rugieri Pacheco S, Magalhães Andrade dos Santos MI, Stocker A, Sant’Anna Zarife MA, Schinoni MI, Paraná R, Galvao dos Reis M, Kalabric Silva L. Genotyping of HBV and tracking of resistance mutations in treatment-naïve patients with chronic hepatitis B. Infect Drug Resist. 2017;10:201–207. https://doi.org/10.2147/IDR.S135420
    [PUBMED] [CROSSREF]
  19. Saran B, Tüzüner U, Feyzïoğlu B, Özdemïr M, Baykan M. Determination of resistance mutation in chronic Hepatitis B patients using antiviral drugs at our hospital. Viral Hepatit Dergisi. 2017;23(1):30–33. https://doi.org/10.4274/vhd.38257
    [CROSSREF]
  20. Sayan M, Buğdaci MS. [HBV vaccine escape mutations in a chronic hepatitis B patient treated with nucleos(t)ide analogues] (in Turkish). Mikrobiyol Bul. 2013;47(3):544–549. https://doi.org/10.5578/mb.5442
    [PUBMED] [CROSSREF]
  21. Sayan M, Cavdar C, Dogan C. Naturally occurring polymerase and surface gene variants of hepatitis B virus in Turkish hemodialysis patients with chronic hepatitis B. Jpn J Infect Dis. 2012;65(6):495–501. https://doi.org/10.7883/yoken.65.495
    [CROSSREF]
  22. Sayan M, Hulagu S, Karatayli SC. Multidrug-resistant hepatitis B virus strain in a chronic Turkish patient. Hepat Mon. 2010a Spring;10(2):141–146.
  23. Sayan M, Şentürk Ö, Akhan SÇ, Hülagü S, Çekmen MB. Monitoring of hepatitis B virus surface antigen escape mutations and concomitantly nucleos(t)ide analog resistance mutations in Turkish patients with chronic hepatitis B. Int J Infect Dis. 2010b; 14 Suppl 3:e136–e141. https://doi.org/10.1016/j.ijid.2009.11.039
    [CROSSREF]
  24. Shaw T, Bartholomeusz A, Locarnini S. HBV drug resistance: Mechanisms, detection and interpretation. J Hepatol. 2006;44(3): 593–606. https://doi.org/10.1016/j.jhep.2006.01.001
    [PUBMED] [CROSSREF]
  25. Sheldon J, Soriano V. Hepatitis B virus escape mutants induced by antiviral therapy. J Antimicrob Chemother. 2008;61(4):766–768. https://doi.org/10.1093/jac/dkn014
    [PUBMED] [CROSSREF]
  26. Simon B, Kundi M, Puchhammer E. Analysis of mutations in the S gene of hepatitis B virus strains in patients with chronic infection by online bioinformatics tools. J Clin Microbiol. 2013;51(1):163–168. https://doi.org/10.1128/JCM.01630-12
    [PUBMED] [CROSSREF]
  27. Suer HK, Guvenir M, Guler E, Diktas H. Evaluation of HBsAg, anti-HCV, anti-HIV and syphilis test results among the blood donors admitted to the Near East University Hospital in Turkish Republic of Northern Cyprus. Klimik Dergisi/Klimik Journal. 2014; 25(3):99–102. https://doi.org/10.5152/kd.2012.28
    [CROSSREF]
  28. Sun M, Tan G, Song J, Wang J, Wu X. Profile of HBV polymerase gene mutations during entecavir treatment in patients with chronic hepatitis B. Clin Res Hepatol Gastroenterol. 2016;40(5):590–596. https://doi.org/10.1016/j.clinre.2016.02.005
    [PUBMED] [CROSSREF]
  29. Tang LSY, Covert E, Wilson E, Kottilil S. Chronic Hepatitis B Infection. JAMA. 2018;319(17):1802–1813. https://doi.org/10.1001/jama.2018.3795
    [CROSSREF]
  30. Tezcan S, Ülger M, Üçbïlek E, Aslan G, Serïn MS, Sezgïn O, Delïalïoğlu N, Altintaş E, Helvaci İ, Emekdaş G. [Characterization of basal core promoter/precore gene mutations in chronically infected patients with hepatitis B virus genotype D in Mersin Province, Turkey] (in Turkish). Mikrobiyol Bul. 2015;49(3):377–392. https://doi.org/10.5578/mb.9479
    [CROSSREF]
  31. Wang J, Zhu B, Lu M, Yang D. Hepatitis B virus preS/S gene mutations and their clinical implications. Ann Blood. 2017;2(17):17. https://doi.org/10.21037/aob.2017.10.01
    [CROSSREF]
  32. Ward H, Tang L, Poonia B, Kottilil S. Treatment of hepatitis B virus: an update. Future Microbiol. 2016;11(12):1581–1597. https://doi.org/10.2217/fmb-2016-0128
    [PUBMED] [CROSSREF]
  33. WHO. Key Facts Sheet [Internet]. Geneva (Switzerland): World Health Organization; 2018 [cited 2018 July]. Available from: https://www.who.int/en/news-room/fact-sheets/detail/hepatitis-b
  34. Yano Y, Azuma T, Hayashi Y. Variations and mutations in the hepatitis B virus genome and their associations with clinical characteristics. World J Hepatol. 2015;7(3):583–592. https://doi.org/10.4254/wjh.v7.i3.583
    [PUBMED] [CROSSREF]
  35. Zaaijer HL, van Hemert FJ, Koppelman MH, Lukashov VV. Independent evolution of overlapping polymerase and surface protein genes of hepatitis B virus. J Gen Virol. 2007;88(8):2137–2143. https://doi.org/10.1099/vir.0.82906-0
    [CROSSREF]
  36. Zhao Y, Wu J, Sun L, Liu G, Li B, Zheng Y, Li X, Tao J. Prevalence of mutations in HBV DNA polymerase gene associated with nucleos(t)ide resistance in treatment-naive patients with Chronic Hepatitis B in Central China. Braz J Infect Dis. 2016;20(2):173–178. https://doi.org/10.1016/j.bjid.2015.12.006
    [CROSSREF]

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