Severe perinatal hemolytic disease due to anti-e

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 37 , ISSUE 2 (Jun 2021) > List of articles

Severe perinatal hemolytic disease due to anti-e

G. Soler-Noda * / Y. Romero-Díaz / L. Orbeal-Aldama / S. Aquino-Rojas

Keywords : hemolytic disease of the fetus and newborn, HDFN, postnatal diagnosis, Rh blood group system, Rhe, Rh5

Citation Information : Immunohematology. Volume 37, Issue 2, Pages 72-77, DOI: https://doi.org/10.21307/immunohematology-2021-011

License : (Transfer of Copyright)

Published Online: 25-June-2021

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ABSTRACT

Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rh system antibodies is a significant cause of hemolytic disease of the fetus and newborn. Here, we report a rare case of severe perinatal hemolytic disease associated with maternal antibody to the e antigen. In addition to severe anemia, the infant developed hyperbilirubinemia. Resolution of the infant’s anemia and hyperbilirubinemia occurred after treatment with phototherapy, intravenous immunoglobulin, and transfusion.

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