Anti-Vel alloimmunization and severe hemolytic disease of the fetus and newborn

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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Volume 33 (2020)
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VOLUME 33 , ISSUE 4 (Mar 2020) > List of articles

Anti-Vel alloimmunization and severe hemolytic disease of the fetus and newborn

K.J. Moise * / Y. Morales / M.F. Bertholf / S.N. Rossmann / Y. Bai

Keywords : anti-Vel, Vel, red blood cell antibody, red blood cell alloimmunization, hemolytic disease of the fetus and newborn, intrauterine transfusion

Citation Information : Immunohematology. Volume 33, Issue 4, Pages 152-154, DOI: https://doi.org/10.21307/immunohematology-2019-021

License : (CC-BY-NC-ND 4.0)

Published Online: 30-March-2020

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ABSTRACT

Only rare cases of anti-Vel–associated mild-to-moderate hemolytic disease of the fetus and newborn have been previously reported. No case of fetal anemia requiring prenatal therapy has been noted to date. We report such a case recently encountered at our Fetal Center. Strategies are discussed for managing pregnancy complicated with alloimmunization to an antibody to a high-prevalence antigen, including sources of red blood cells for intrauterine transfusions.

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